Chloro-5-iodo-6-methylpyrimidin-2-amine, 4-

Chloro-5-iodo-6-methylpyrimidin-2-amine, 4- - Names and Identifiers

Name	4-chloro-5-iodo-6-methylpyrimidin-2-amine
Synonyms	4-Chloro-5-iodo-6-methylpyrimidin-2-amine 4-chloro-5-iodo-6-methylpyrimidin-2-amine 2-Amino-4-chloro-5-iodo-6-methylpyrimidine 2-Pyrimidinamine, 4-chloro-5-iodo-6-methyl- 2-pyrimidinamine, 4-chloro-5-iodo-6-methyl- Chloro-5-iodo-6-methylpyrimidin-2-amine, 4- 4-chloro-5-iodo-6-methyl-pyrimidin-2-ylamine 4-Chloro-5-iodo-6-methylpyrimidin-2-amine, 2-Amino-4-chloro-5-iodo-6-methyl-1,3-diazine
CAS	897030-99-8
InChI	InChI=1/C5H5ClIN3/c1-2-3(7)4(6)10-5(8)9-2/h1H3,(H2,8,9,10)

Chloro-5-iodo-6-methylpyrimidin-2-amine, 4- - Physico-chemical Properties

Molecular Formula	C5H5ClIN3
Molar Mass	269.47
Density	2.098g/cm³
Melting Point	197～199℃
Boling Point	406.809°C at 760 mmHg
Flash Point	199.831°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.694

Chloro-5-iodo-6-methylpyrimidin-2-amine, 4- - Introduction

It is an organic compound with CAS No. 1405882-02-6. Its chemical formula is C6H5ClIN3 and its relative molecular mass is 312.48.

The following are some of the properties of the pill:

1. Appearance: colorless or light yellow crystalline powder;
2. Melting point: about 175-177°C;
3. Solubility: insoluble in water, better solubility in some organic solvents.

It is often used in organic synthesis, for example, as an important intermediate for the preparation of drugs, dyes and pesticides and other compounds. It can be used as an intermediate of anticancer drugs in pharmacy, and is used to synthesize polypeptide antitumor drugs. In addition, it can also be used for the preparation of biomarkers and antibacterial agents.

There are a variety of methods for preparing, and common methods include reacting 2-chloro-4-amino-5-iodo-6-methylpyrimidine with a base, or by reacting chlorine and iodine on the amino group in the replacement reaction.

The following safety information needs to be paid attention to when using the metal:

1. Avoid contact with skin, eyes and respiratory tract. Protective gloves, goggles and masks shall be worn during operation;
2. If exposed to the compound, rinse immediately with plenty of water;
3. storage should be sealed, avoid contact with oxygen, acid, alkali and other substances;
4. maintain good ventilation during operation and storage;
5. comply with the chemical laboratory safety practices.

Last Update：2024-04-09 21:21:28